NIH
The purpose of this Notice of Funding Opportunity (NOFO) is to promote the discovery, development, and validation of real-world digital endpoints derived from data generated by existing remote or wearable devices. These endpoints will be used for monitoring the experience of pain, its progression, response to interventions, and impact on quality of life. Applications aiming to identify digital endpoints across various pain conditions should involve Multiple Principal Investigator (MPI)-led teams that represent each relevant pain condition and associated clinical networks. In addition, the applicant should include experts in digital technology, data analysis, and advanced statistical methods to handle real-world data.