Mid-scale RI-2 projects may include any combination of equipment, instrumentation, cyberinfrastructure, broadly used large-scale data sets, and the commissioning and/or personnel needed to successfully complete the project. Mid-scale RI-2 projects should fill a research community-defined scientific need, or address an identified national research priority, that enables current and next-generation U.S. researchers and a diverse STEM workforce to remain competitive in a global research environment. Mid-scale RI-2 projects will directly enable advances in any of the research domains supported by NSF, including STEM education research, and translational research. Projects may also include upgrades to existing research infrastructure. The total cost for Mid-scale RI-2 projects ranges from $20 million to below the threshold for a Major Facility Project, currently $100 million.