The CDS&E meta-program supports projects that harness computation and data to advance knowledge and accelerate discovery above and beyond the goals of the participating individual programs. A CDS&E proposal should include substantive research in science, engineering, or computing. Algorithm and pilot software development supporting science and engineering may also be appropriate, depending on the program. In picking the most relevant program, PIs are advised to read program descriptions and solicitations carefully and to consult with cognizant Program Officers in advance of proposal preparation. Proposal submissions outside of the scientific scope of the receiving program may be transferred to a different program or may be returned without review.